Metabolic & Weight Management

5-Amino-1MQ

Also known as 5-amino-1-methylquinolinium · NNMT inhibitor

PreliminaryOralNot FDA-approved; research compound with limited published human data. Not an approved drug; sometimes sold as a research chemical or via compounding.

5-Amino-1MQ is a small-molecule inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT), which is highly expressed in adipose tissue. By inhibiting NNMT, it is proposed to shift cellular metabolism toward increased energy expenditure and fat oxidation. Evidence is largely preclinical, consisting of cell and rodent studies, with little to no published human trial data.

Studied / used for

researched for fat accumulation and diet-induced obesity in animal models
researched for cellular energy metabolism and lipid profiles

Commonly reported side effects

human safety data is limited or not established
side-effect profile in humans not well characterized

Preliminary. Mostly early or animal studies. This reflects the strength of the research base, not effectiveness or a recommendation.

Not medical advice.

This is an educational reference. Peptalk does not recommend, prescribe, endorse, or rate any compound, and provides no dosing information. Do not start, stop, or change any peptide, hormone, supplement, or therapy based on this page. All clinical decisions must be made with your licensed healthcare provider.

← Back to all compounds