Peptalk

Educational reference

Explore peptides & wellness compounds.

What each compound is, what it is studied or used for, commonly reported side effects, and how strong the underlying evidence is. A neutral starting point for a conversation with your provider.

Educational only — not medical advice.

Peptalk does not recommend, prescribe, endorse, or rate any compound. The evidence level shown describes the strength of the research base — not effectiveness, safety, or a recommendation. No dosing information is provided. Do not start, stop, or change any therapy based on this page. Always consult your licensed healthcare provider.

101 of 101 compounds

Anastrozole

Arimidex

Aromatase inhibitor used off-label in men to limit conversion of testosterone to estrogen.

Clinically studiedHormones & TRT/HRT Adjuncts

ARA-290 (Cibinetide)

Cibinetide · Erythropoietin-derived peptide

Erythropoietin-derived 11-amino-acid peptide studied in trials for small-fiber neuropathy.

Clinically studiedTissue Repair & Recovery

CagriSema

cagrilintide/semaglutide · cagri-sema

An investigational once-weekly fixed-dose combination of an amylin analogue and a GLP-1 receptor agonist.

Clinically studiedMetabolic & Weight Management

Clomiphene Citrate

Clomid · Serophene

SERM used off-label to stimulate endogenous testosterone in men.

Clinically studiedSexual & Reproductive Health

Dulaglutide

Trulicity

Once-weekly GLP-1 receptor agonist studied for type 2 diabetes.

Clinically studiedMetabolic & Weight Management

Enclomiphene Citrate

enclomifene · Androxal

Selective estrogen receptor modulator studied to raise testosterone while preserving fertility.

Clinically studiedHormones & TRT/HRT Adjuncts

Estradiol

17 beta-estradiol · E2

Primary estrogen hormone used in menopausal and gender-affirming hormone therapy.

Clinically studiedHormones & TRT/HRT Adjuncts

Exenatide

Byetta · Bydureon

GLP-1 receptor agonist studied for type 2 diabetes glycemic control.

Clinically studiedMetabolic & Weight Management

Gonadorelin

GnRH · LHRH

Synthetic GnRH studied for stimulating the pituitary-gonadal axis.

Clinically studiedSexual & Reproductive Health

HCG (Human Chorionic Gonadotropin)

hCG · Human Chorionic Gonadotropin

Gonadotropin that mimics LH, studied for testicular function and fertility.

Clinically studiedSexual & Reproductive Health

HGH 191AA (Somatropin)

HGH 191AA · Human Growth Hormone

Recombinant 191-amino-acid human growth hormone, FDA-approved for several growth-hormone-deficiency and wasting conditions.

Clinically studiedHormones & TRT/HRT Adjuncts

Human Chorionic Gonadotropin (hCG)

hCG · chorionic gonadotropin

Gonadotropin hormone that mimics LH to stimulate testicular testosterone production.

Clinically studiedHormones & TRT/HRT Adjuncts

Larazotide

Larazotide acetate · AT-1001

Synthetic octapeptide studied as a gut tight-junction regulator that acts locally in the intestine.

Clinically studiedTissue Repair & Recovery

Liraglutide

Victoza · Saxenda

Daily GLP-1 receptor agonist studied for diabetes and weight management.

Clinically studiedMetabolic & Weight Management

Maridebart cafraglutide

MariTide · AMG 133

Investigational long-acting GLP-1 receptor agonist and GIP receptor antagonist studied for obesity.

Clinically studiedMetabolic & Weight Management

Mazdutide

IBI362 · LY3305677

A synthetic oxyntomodulin analog that acts as a dual GLP-1 and glucagon receptor agonist.

Clinically studiedMetabolic & Weight Management

Melanotan I

Melanotan-1 · MT-1

A synthetic alpha-MSH analog that activates the MC1 receptor to increase skin pigmentation.

Clinically studiedCosmetic & Skin

Orforglipron

Foundayo · orfo

Oral, non-peptide small-molecule GLP-1 receptor agonist studied for weight management and type 2 diabetes.

Clinically studiedMetabolic & Weight Management

Pentosan Polysulfate Sodium

PPS · Elmiron

FDA-approved semi-synthetic polysaccharide studied off-label for joint and cartilage protection.

Clinically studiedTissue Repair & Recovery

Progesterone (Micronized)

micronized progesterone · Prometrium

Endogenous steroid hormone used in HRT, often to protect the uterine lining.

Clinically studiedHormones & TRT/HRT Adjuncts

PT-141 (Bremelanotide)

Bremelanotide · Vyleesi

Melanocortin receptor agonist studied for sexual desire and arousal.

Clinically studiedSexual & Reproductive Health

Semaglutide

Ozempic · Wegovy

GLP-1 receptor agonist studied for glycemic control and weight management.

Clinically studiedMetabolic & Weight Management

SS-31 (Elamipretide)

SS-31 · Elamipretide

Mitochondria-targeting tetrapeptide that stabilizes cardiolipin in the inner membrane.

Clinically studiedLongevity & Mitochondrial

Tesamorelin

Tesamorelin acetate · Egrifta

FDA-approved GHRH analog for excess abdominal fat in HIV-associated lipodystrophy.

Clinically studiedGrowth Hormone Secretagogues

Testosterone Cypionate

Depo-Testosterone · Test C

Long-acting injectable testosterone ester used as replacement therapy in men.

Clinically studiedHormones & TRT/HRT Adjuncts

Testosterone Enanthate

Test E · Xyosted

Long-acting injectable testosterone ester used as replacement therapy in men.

Clinically studiedHormones & TRT/HRT Adjuncts

Thymosin Alpha-1

Ta1 · Tα1

Thymic peptide studied as an immune modulator and vaccine adjuvant.

Clinically studiedImmune & Thymic

Thymosin Beta-4 (Tβ4)

TB4 · Thymosin β4

Naturally occurring 43-amino-acid regenerative peptide with an ophthalmic drug program studied in controlled human trials.

Clinically studiedTissue Repair & Recovery

Tirzepatide

Mounjaro · Zepbound

Dual GIP/GLP-1 receptor agonist studied for diabetes and weight management.

Clinically studiedMetabolic & Weight Management

Amycretin

NN-9487 · NN9487

Investigational single-molecule GLP-1 and amylin receptor agonist studied for obesity and type 2 diabetes.

Emerging researchMetabolic & Weight Management

Bimagrumab

BYM338 · Versanis drug

Investigational monoclonal antibody blocking activin type II receptors, studied for fat loss with muscle preservation.

Emerging researchMetabolic & Weight Management

BPC-157

Body Protection Compound 157 · Bepecin

Synthetic gastric pentadecapeptide studied for soft-tissue and gut healing in animal models.

Emerging researchTissue Repair & Recovery

Cagrilintide

AM833 · long-acting amylin analog

Investigational long-acting amylin analog studied for weight management.

Emerging researchMetabolic & Weight Management

Cerebrolysin

FPF-1070 · Porcine brain peptide preparation

Porcine-brain-derived peptide mixture studied for dementia, stroke, and TBI.

Emerging researchCognitive & Neuro

DHEA

dehydroepiandrosterone · prasterone

Adrenal steroid precursor to testosterone and estrogen, sold mostly as a supplement.

Emerging researchHormones & TRT/HRT Adjuncts

Enclomiphene Citrate

Enclomiphene · Androxal

SERM studied for raising testosterone while preserving fertility in men.

Emerging researchSexual & Reproductive Health

Follistatin-344

FS-344 · FST-344

Full-length follistatin precursor (FS344) studied for binding myostatin and activin to influence muscle-growth signaling.

Emerging researchGrowth Factors & IGF

GHK-Cu

Copper tripeptide-1 · Copper peptide

Copper-binding tripeptide studied topically for skin renewal and wound healing.

Emerging researchTissue Repair & Recovery

GHRP-2

Growth Hormone Releasing Peptide-2 · Pralmorelin

Synthetic ghrelin-receptor agonist studied for growth-hormone release.

Emerging researchGrowth Hormone Secretagogues

Glutathione

Glutathione · GSH

Endogenous antioxidant tripeptide central to cellular redox balance and detoxification.

Emerging researchLongevity & Mitochondrial

Kisspeptin-10

Kisspeptin · KP-10

Hypothalamic neuropeptide studied for reproductive-axis and sexual brain signaling.

Emerging researchSexual & Reproductive Health

L-Carnitine / Acetyl-L-Carnitine

L-Carnitine · Acetyl-L-carnitine

Amino-acid derivative that shuttles fatty acids into mitochondria for energy production.

Emerging researchLongevity & Mitochondrial

LL-37

Cathelicidin · CAP-18 fragment

The sole human cathelicidin antimicrobial peptide with immune-modulating roles.

Emerging researchImmune & Thymic

Matrixyl (Palmitoyl Pentapeptide-4)

Palmitoyl Pentapeptide-4 · Palmitoyl Pentapeptide-3

A topical signal peptide used in anti-aging cosmetics to influence skin matrix proteins.

Emerging researchCosmetic & Skin

Matrixyl 3000

Palmitoyl Pentapeptide blend · Pal-GHK + Pal-GQPR

A topical cosmetic matrikine peptide blend studied for the appearance of aging skin.

Emerging researchCosmetic & Skin

MK-677 (Ibutamoren)

Ibutamoren · Ibutamoren mesylate

Orally active ghrelin-receptor agonist studied for non-pulsatile GH and IGF-1 elevation.

Emerging researchGrowth Hormone Secretagogues

NAD+ (Nicotinamide Adenine Dinucleotide)

NAD · NAD+

Coenzyme central to mitochondrial energy production whose tissue levels decline with age.

Emerging researchLongevity & Mitochondrial

NMN / NR (NAD+ Precursors)

NMN · Nicotinamide mononucleotide

Vitamin B3-related precursors that the body converts into NAD+.

Emerging researchLongevity & Mitochondrial

Oxytocin

Pitocin · Syntocinon

Endogenous hormone studied for bonding, intimacy, and orgasm-related effects.

Emerging researchSexual & Reproductive Health

Pemvidutide

ALT-801

An investigational injectable GLP-1/glucagon dual receptor agonist studied for obesity and fatty liver disease.

Emerging researchMetabolic & Weight Management

Petrelintide

ZP8396 · long-acting amylin analog

Investigational long-acting amylin analog being developed as a once-weekly injection for weight management.

Emerging researchMetabolic & Weight Management

Retatrutide

LY3437943 · triple-G agonist

Investigational triple GIP/GLP-1/glucagon receptor agonist studied for obesity.

Emerging researchMetabolic & Weight Management

Selank

Thr-Lys-Pro-Arg-Pro-Gly-Pro · Tuftsin analog

Synthetic tuftsin-derived heptapeptide studied as a non-sedating anxiolytic.

Emerging researchCognitive & Neuro

Semax

ACTH(4-10) analog · Met-Glu-His-Phe-Pro-Gly-Pro

Russian-developed ACTH(4-10) analog studied as a nootropic and neuroprotective peptide.

Emerging researchCognitive & Neuro

Sermorelin

Sermorelin acetate · GRF 1-29

GHRH analog peptide that prompts the pituitary to release growth hormone.

Emerging researchGrowth Hormone Secretagogues

SNAP-8

Acetyl Octapeptide-3 · Acetyl Glutamyl Heptapeptide-3

A synthetic octapeptide studied as a topical cosmetic ingredient for the look of expression lines.

Emerging researchCosmetic & Skin

Spermidine

Spermidine trihydrochloride · Spermidine-rich wheat germ extract

A naturally occurring dietary polyamine studied as an autophagy inducer in aging research.

Emerging researchLongevity & Mitochondrial

Survodutide

BI 456906 · BI-456906

Investigational dual GLP-1/glucagon receptor agonist studied for obesity and metabolic liver disease.

Emerging researchMetabolic & Weight Management

Tesofensine

NS2330

Investigational triple monoamine reuptake inhibitor studied for obesity.

Emerging researchMetabolic & Weight Management

Thymopentin

TP-5 · TP5

Pentapeptide fragment of thymopoietin studied for restoring T-cell function.

Emerging researchImmune & Thymic

Urolithin A

UroA · UA

Gut-derived metabolite of dietary ellagitannins studied as a mitophagy inducer for mitochondrial health.

Emerging researchLongevity & Mitochondrial

VIP (Vasoactive Intestinal Peptide)

Vasoactive Intestinal Polypeptide · Aviptadil (synthetic form)

Naturally occurring 28-amino-acid peptide studied for broad anti-inflammatory effects.

Emerging researchTissue Repair & Recovery

5-Amino-1MQ

5-amino-1-methylquinolinium · NNMT inhibitor

Small-molecule NNMT inhibitor researched for fat metabolism.

PreliminaryMetabolic & Weight Management

Adipotide

FTPP · Fat-Targeted Proapoptotic Peptide

Experimental peptidomimetic designed to target the blood vessels supplying white fat tissue.

PreliminaryMetabolic & Weight Management

AOD-9604

HGH fragment 176-191 · growth hormone fragment

Synthetic growth-hormone fragment researched for fat metabolism.

PreliminaryMetabolic & Weight Management

Argireline

Acetyl Hexapeptide-8 · Acetyl Hexapeptide-3

A synthetic peptide studied in topical cosmetics for the look of expression lines.

PreliminaryCosmetic & Skin

CJC-1295 (no DAC)

CJC-1295 without DAC · Mod GRF 1-29

Short-acting modified GHRH analog studied as a pulsatile growth-hormone stimulus.

PreliminaryGrowth Hormone Secretagogues

CJC-1295 with DAC

CJC-1295 DAC · Drug Affinity Complex CJC-1295

Long-acting GHRH analog studied for sustained growth-hormone elevation.

PreliminaryGrowth Hormone Secretagogues

Dihexa

N-hexanoic-Tyr-Ile-(6) aminohexanoic amide · PNB-0408

Angiotensin IV-derived peptidomimetic studied in preclinical models for synaptogenesis.

PreliminaryCognitive & Neuro

DSIP (Delta Sleep-Inducing Peptide)

Delta Sleep-Inducing Peptide · Emideltide

A naturally occurring nonapeptide studied for sleep regulation, with mixed human evidence.

PreliminarySleep & Recovery

FOXO4-DRI

FOXO4-DRI · FOXO4 D-Retro-Inverso peptide

Senolytic peptide designed to selectively trigger apoptosis in senescent cells.

PreliminaryLongevity & Mitochondrial

GHK (copper-free)

Glycyl-L-Histidyl-L-Lysine · GHK tripeptide

A naturally occurring human tripeptide studied in skin care in its non-copper-bound form.

PreliminaryCosmetic & Skin

GHRP-6

Growth Hormone Releasing Peptide-6 · SKF-110679

Early clinically studied GHRP; ghrelin-receptor agonist with marked appetite effect.

PreliminaryGrowth Hormone Secretagogues

Hexarelin

Examorelin · EP-23905

Synthetic GHRP analog studied for growth-hormone and cardiovascular effects.

PreliminaryGrowth Hormone Secretagogues

HGH Fragment 176-191

Frag 176-191 · HGH Frag

A synthetic C-terminal fragment of human growth hormone studied for fat metabolism in research settings.

PreliminaryMetabolic & Weight Management

Humanin

Humanin · HN

Mitochondrial-derived peptide that acts as a cytoprotective and neuroprotective signal.

PreliminaryLongevity & Mitochondrial

IGF-1 DES

IGF-1 DES(1-3) · DES(1-3) IGF-1

A truncated analog of IGF-1 studied chiefly in cell and animal models for localized growth signaling.

PreliminaryGrowth Factors & IGF

IGF-1 LR3

Long R3 IGF-1 · Long Arg3 IGF-1

A long-acting synthetic analog of insulin-like growth factor 1 used chiefly as a research reagent.

PreliminaryGrowth Factors & IGF

Ipamorelin

NNC 26-0161

Selective ghrelin-receptor agonist that stimulates a growth-hormone pulse.

PreliminaryGrowth Hormone Secretagogues

Klotho

Klotho protein · alpha-Klotho

A naturally occurring protein, first linked to aging in mice, studied as a longevity and cognition factor.

PreliminaryLongevity & Mitochondrial

KPV

Lysine-Proline-Valine · α-MSH (11-13)

Alpha-MSH-derived tripeptide studied for anti-inflammatory effects in the gut and skin.

PreliminaryTissue Repair & Recovery

Lipo-B12 / MIC Injection

Lipotropic injection · MIC

A compounded lipotropic blend combining methionine, inositol, choline, and vitamin B12.

PreliminaryMetabolic & Weight Management

MGF (Mechano Growth Factor)

Mechano Growth Factor · IGF-1Ec

A locally expressed IGF-1 splice variant studied in animal models for muscle repair.

PreliminaryGrowth Factors & IGF

MOTS-c

Mitochondrial ORF of the twelve S rRNA type-c · mitochondrial-derived peptide

Mitochondrial-derived peptide researched for metabolic regulation.

PreliminaryMetabolic & Weight Management

P21 (P021)

P021 · P-21

Adamantane-modified CNTF-derived tetrapeptide studied for neurogenesis and tau pathology.

PreliminaryCognitive & Neuro

Palmitoyl Tetrapeptide-7

Pal-GQPR · Rigin

A synthetic topical lipopeptide studied as an anti-inflammatory, skin-conditioning ingredient in cosmetic formulations.

PreliminaryCosmetic & Skin

Palmitoyl Tripeptide-1

Pal-GHK · Palmitoyl Oligopeptide

A topical cosmetic peptide studied as a fibroblast-signaling ingredient in anti-aging skincare formulations.

PreliminaryCosmetic & Skin

PE-22-28

Spadin analog · TREK-1 inhibitor peptide

Spadin-derived 7-residue peptide studied for antidepressant-like effects via TREK-1.

PreliminaryCognitive & Neuro

PEG-MGF

Pegylated MGF · Pegylated Mechano Growth Factor

A pegylated, longer-acting form of a muscle-derived IGF-1 splice variant studied mainly in preclinical models.

PreliminaryGrowth Factors & IGF

Pinealon

Pineal bioregulator · EDR peptide

A synthetic Glu-Asp-Arg tripeptide bioregulator studied in laboratory models for neuroprotection and gene-expression effects.

PreliminaryCognitive & Neuro

Pregnenolone

P5 · 3 beta-hydroxy-5-pregnen-20-one

Upstream steroid precursor hormone sold as a supplement with limited evidence.

PreliminaryHormones & TRT/HRT Adjuncts

SLU-PP-332

ERR agonist · exercise mimetic

An experimental synthetic ERR agonist studied in animals as an "exercise mimetic" for metabolic pathways.

PreliminaryLongevity & Mitochondrial

TB-500

Thymosin Beta-4 fragment · TB4 synthetic analog

Synthetic peptide related to thymosin beta-4, studied for cell migration and soft-tissue recovery.

PreliminaryTissue Repair & Recovery

Thymalin

Thymus peptide complex · Thymalinum

Calf-thymus peptide complex used in Russia as an immune bioregulator.

PreliminaryImmune & Thymic

Thymogen

Thymagen · Glu-Trp

Synthetic dipeptide (Glu-Trp) derived from thymalin as a minimal immune regulator.

PreliminaryImmune & Thymic

Thymulin

Thymulin · Zinc-thymulin

Zinc-dependent thymic nonapeptide involved in T-cell maturation and immune signaling.

PreliminaryLongevity & Mitochondrial

Epitalon (Epithalon)

Epitalon · Epithalon

Synthetic pineal tetrapeptide studied for telomerase activation and circadian regulation.

AnecdotalLongevity & Mitochondrial

Melanotan II

MT-II · MT2

Non-selective melanocortin agonist associated with pigmentation and arousal effects.

AnecdotalSexual & Reproductive Health

N-Acetyl Selank Amidate

NA-Selank Amidate · NA Selank

Modified Selank variant engineered for improved enzymatic stability.

AnecdotalCognitive & Neuro

N-Acetyl Semax Amidate

NA-Semax Amidate · NA Semax

Chemically modified Semax variant designed for greater stability and longer action.

AnecdotalCognitive & Neuro

Pentadeca Arginate (PDA)

PDA · BPC-157 arginate

Arginate-salt form of the BPC-157 sequence sold for healing; lacks its own trial data.

AnecdotalTissue Repair & Recovery

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