Peptalk

Educational reference

Explore peptides & wellness compounds.

What each compound is, what it is studied or used for, commonly reported side effects, and how strong the underlying evidence is. A neutral starting point for a conversation with your provider.

Educational only — not medical advice.

Peptalk does not recommend, prescribe, endorse, or rate any compound. The evidence level shown describes the strength of the research base — not effectiveness, safety, or a recommendation. No dosing information is provided. Do not start, stop, or change any therapy based on this page. Always consult your licensed healthcare provider.

99 of 99 compounds

Anastrozole

Arimidex

→

Aromatase inhibitor used off-label in men to limit conversion of testosterone to estrogen.

Clinically studiedHormones & TRT/HRT Adjuncts

ARA-290 (Cibinetide)

Cibinetide · Erythropoietin-derived peptide

→

Erythropoietin-derived 11-amino-acid peptide studied in trials for small-fiber neuropathy.

Clinically studiedTissue Repair & Recovery

CagriSema

cagrilintide/semaglutide · cagri-sema

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An investigational once-weekly fixed-dose combination of an amylin analogue and a GLP-1 receptor agonist.

Clinically studiedMetabolic & Weight Management

Clomiphene Citrate

Clomid · Serophene

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SERM used off-label to stimulate endogenous testosterone in men.

Clinically studiedSexual & Reproductive Health

Dulaglutide

Trulicity

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Once-weekly GLP-1 receptor agonist studied for type 2 diabetes.

Clinically studiedMetabolic & Weight Management

Enclomiphene Citrate

enclomifene · Androxal

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Selective estrogen receptor modulator studied to raise testosterone while preserving fertility.

Clinically studiedHormones & TRT/HRT Adjuncts

Estradiol

17 beta-estradiol · E2

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Primary estrogen hormone used in menopausal and gender-affirming hormone therapy.

Clinically studiedHormones & TRT/HRT Adjuncts

Exenatide

Byetta · Bydureon

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GLP-1 receptor agonist studied for type 2 diabetes glycemic control.

Clinically studiedMetabolic & Weight Management

Gonadorelin

GnRH · LHRH

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Synthetic GnRH studied for stimulating the pituitary-gonadal axis.

Clinically studiedSexual & Reproductive Health

HGH 191AA (Somatropin)

HGH 191AA · Human Growth Hormone

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Recombinant 191-amino-acid human growth hormone, FDA-approved for several growth-hormone-deficiency and wasting conditions.

Clinically studiedHormones & TRT/HRT Adjuncts

Human Chorionic Gonadotropin (hCG)

hCG · chorionic gonadotropin

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Gonadotropin hormone that mimics LH to stimulate testicular testosterone production.

Clinically studiedHormones & TRT/HRT Adjuncts

Larazotide

Larazotide acetate · AT-1001

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Synthetic octapeptide studied as a gut tight-junction regulator that acts locally in the intestine.

Clinically studiedTissue Repair & Recovery

Liraglutide

Victoza · Saxenda

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Daily GLP-1 receptor agonist studied for diabetes and weight management.

Clinically studiedMetabolic & Weight Management

Maridebart cafraglutide

MariTide · AMG 133

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Investigational long-acting GLP-1 receptor agonist and GIP receptor antagonist studied for obesity.

Clinically studiedMetabolic & Weight Management

Mazdutide

IBI362 · LY3305677

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A synthetic oxyntomodulin analog that acts as a dual GLP-1 and glucagon receptor agonist.

Clinically studiedMetabolic & Weight Management

Melanotan I

Melanotan-1 · MT-1

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A synthetic alpha-MSH analog that activates the MC1 receptor to increase skin pigmentation.

Clinically studiedCosmetic & Skin

Orforglipron

Foundayo · orfo

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Oral, non-peptide small-molecule GLP-1 receptor agonist studied for weight management and type 2 diabetes.

Clinically studiedMetabolic & Weight Management

Pentosan Polysulfate Sodium

PPS · Elmiron

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FDA-approved semi-synthetic polysaccharide studied off-label for joint and cartilage protection.

Clinically studiedTissue Repair & Recovery

Progesterone (Micronized)

micronized progesterone · Prometrium

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Endogenous steroid hormone used in HRT, often to protect the uterine lining.

Clinically studiedHormones & TRT/HRT Adjuncts

PT-141 (Bremelanotide)

Bremelanotide · Vyleesi

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Melanocortin receptor agonist studied for sexual desire and arousal.

Clinically studiedSexual & Reproductive Health

Semaglutide

Ozempic · Wegovy

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GLP-1 receptor agonist studied for glycemic control and weight management.

Clinically studiedMetabolic & Weight Management

SS-31 (Elamipretide)

SS-31 · Elamipretide

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Mitochondria-targeting tetrapeptide that stabilizes cardiolipin in the inner membrane.

Clinically studiedLongevity & Mitochondrial

Tesamorelin

Tesamorelin acetate · Egrifta

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FDA-approved GHRH analog for excess abdominal fat in HIV-associated lipodystrophy.

Clinically studiedGrowth Hormone Secretagogues

Testosterone Cypionate

Depo-Testosterone · Test C

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Long-acting injectable testosterone ester used as replacement therapy in men.

Clinically studiedHormones & TRT/HRT Adjuncts

Testosterone Enanthate

Test E · Xyosted

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Long-acting injectable testosterone ester used as replacement therapy in men.

Clinically studiedHormones & TRT/HRT Adjuncts

Thymosin Alpha-1

Ta1 · Tα1

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Thymic peptide studied as an immune modulator and vaccine adjuvant.

Clinically studiedImmune & Thymic

Thymosin Beta-4 (Tβ4)

TB4 · Thymosin β4

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Naturally occurring 43-amino-acid regenerative peptide with an ophthalmic drug program studied in controlled human trials.

Clinically studiedTissue Repair & Recovery

Tirzepatide

Mounjaro · Zepbound

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Dual GIP/GLP-1 receptor agonist studied for diabetes and weight management.

Clinically studiedMetabolic & Weight Management

Amycretin

NN-9487 · NN9487

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Investigational single-molecule GLP-1 and amylin receptor agonist studied for obesity and type 2 diabetes.

Emerging researchMetabolic & Weight Management

Bimagrumab

BYM338 · Versanis drug

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Investigational monoclonal antibody blocking activin type II receptors, studied for fat loss with muscle preservation.

Emerging researchMetabolic & Weight Management

BPC-157

Body Protection Compound 157 · Bepecin

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Synthetic gastric pentadecapeptide studied for soft-tissue and gut healing in animal models.

Emerging researchTissue Repair & Recovery

Cagrilintide

AM833 · long-acting amylin analog

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Investigational long-acting amylin analog studied for weight management.

Emerging researchMetabolic & Weight Management

Cerebrolysin

FPF-1070 · Porcine brain peptide preparation

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Porcine-brain-derived peptide mixture studied for dementia, stroke, and TBI.

Emerging researchCognitive & Neuro

DHEA

dehydroepiandrosterone · prasterone

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Adrenal steroid precursor to testosterone and estrogen, sold mostly as a supplement.

Emerging researchHormones & TRT/HRT Adjuncts

Follistatin-344

FS-344 · FST-344

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Full-length follistatin precursor (FS344) studied for binding myostatin and activin to influence muscle-growth signaling.

Emerging researchGrowth Factors & IGF

GHK-Cu

Copper tripeptide-1 · Copper peptide

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Copper-binding tripeptide studied topically for skin renewal and wound healing.

Emerging researchTissue Repair & Recovery

GHRP-2

Growth Hormone Releasing Peptide-2 · Pralmorelin

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Synthetic ghrelin-receptor agonist studied for growth-hormone release.

Emerging researchGrowth Hormone Secretagogues

Glutathione

Glutathione · GSH

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Endogenous antioxidant tripeptide central to cellular redox balance and detoxification.

Emerging researchLongevity & Mitochondrial

Kisspeptin-10

Kisspeptin · KP-10

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Hypothalamic neuropeptide studied for reproductive-axis and sexual brain signaling.

Emerging researchSexual & Reproductive Health

L-Carnitine / Acetyl-L-Carnitine

L-Carnitine · Acetyl-L-carnitine

→

Amino-acid derivative that shuttles fatty acids into mitochondria for energy production.

Emerging researchLongevity & Mitochondrial

LL-37

Cathelicidin · CAP-18 fragment

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The sole human cathelicidin antimicrobial peptide with immune-modulating roles.

Emerging researchImmune & Thymic

Matrixyl (Palmitoyl Pentapeptide-4)

Palmitoyl Pentapeptide-4 · Palmitoyl Pentapeptide-3

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A topical signal peptide used in anti-aging cosmetics to influence skin matrix proteins.

Emerging researchCosmetic & Skin

Matrixyl 3000

Palmitoyl Pentapeptide blend · Pal-GHK + Pal-GQPR

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A topical cosmetic matrikine peptide blend studied for the appearance of aging skin.

Emerging researchCosmetic & Skin

MK-677 (Ibutamoren)

Ibutamoren · Ibutamoren mesylate

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Orally active ghrelin-receptor agonist studied for non-pulsatile GH and IGF-1 elevation.

Emerging researchGrowth Hormone Secretagogues

NAD+ (Nicotinamide Adenine Dinucleotide)

NAD · NAD+

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Coenzyme central to mitochondrial energy production whose tissue levels decline with age.

Emerging researchLongevity & Mitochondrial

NMN / NR (NAD+ Precursors)

NMN · Nicotinamide mononucleotide

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Vitamin B3-related precursors that the body converts into NAD+.

Emerging researchLongevity & Mitochondrial

Oxytocin

Pitocin · Syntocinon

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Endogenous hormone studied for bonding, intimacy, and orgasm-related effects.

Emerging researchSexual & Reproductive Health

Pemvidutide

ALT-801

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An investigational injectable GLP-1/glucagon dual receptor agonist studied for obesity and fatty liver disease.

Emerging researchMetabolic & Weight Management

Petrelintide

ZP8396 · long-acting amylin analog

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Investigational long-acting amylin analog being developed as a once-weekly injection for weight management.

Emerging researchMetabolic & Weight Management

Retatrutide

LY3437943 · triple-G agonist

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Investigational triple GIP/GLP-1/glucagon receptor agonist studied for obesity.

Emerging researchMetabolic & Weight Management

Selank

Thr-Lys-Pro-Arg-Pro-Gly-Pro · Tuftsin analog

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Synthetic tuftsin-derived heptapeptide studied as a non-sedating anxiolytic.

Emerging researchCognitive & Neuro

Semax

ACTH(4-10) analog · Met-Glu-His-Phe-Pro-Gly-Pro

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Russian-developed ACTH(4-10) analog studied as a nootropic and neuroprotective peptide.

Emerging researchCognitive & Neuro

Sermorelin

Sermorelin acetate · GRF 1-29

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GHRH analog peptide that prompts the pituitary to release growth hormone.

Emerging researchGrowth Hormone Secretagogues

SNAP-8

Acetyl Octapeptide-3 · Acetyl Glutamyl Heptapeptide-3

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A synthetic octapeptide studied as a topical cosmetic ingredient for the look of expression lines.

Emerging researchCosmetic & Skin

Spermidine

Spermidine trihydrochloride · Spermidine-rich wheat germ extract

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A naturally occurring dietary polyamine studied as an autophagy inducer in aging research.

Emerging researchLongevity & Mitochondrial

Survodutide

BI 456906 · BI-456906

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Investigational dual GLP-1/glucagon receptor agonist studied for obesity and metabolic liver disease.

Emerging researchMetabolic & Weight Management

Tesofensine

NS2330

→

Investigational triple monoamine reuptake inhibitor studied for obesity.

Emerging researchMetabolic & Weight Management

Thymopentin

TP-5 · TP5

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Pentapeptide fragment of thymopoietin studied for restoring T-cell function.

Emerging researchImmune & Thymic

Urolithin A

UroA · UA

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Gut-derived metabolite of dietary ellagitannins studied as a mitophagy inducer for mitochondrial health.

Emerging researchLongevity & Mitochondrial

VIP (Vasoactive Intestinal Peptide)

Vasoactive Intestinal Polypeptide · Aviptadil (synthetic form)

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Naturally occurring 28-amino-acid peptide studied for broad anti-inflammatory effects.

Emerging researchTissue Repair & Recovery

5-Amino-1MQ

5-amino-1-methylquinolinium · NNMT inhibitor

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Small-molecule NNMT inhibitor researched for fat metabolism.

PreliminaryMetabolic & Weight Management

Adipotide

FTPP · Fat-Targeted Proapoptotic Peptide

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Experimental peptidomimetic designed to target the blood vessels supplying white fat tissue.

PreliminaryMetabolic & Weight Management

AOD-9604

HGH fragment 176-191 · growth hormone fragment

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Synthetic growth-hormone fragment researched for fat metabolism.

PreliminaryMetabolic & Weight Management

Argireline

Acetyl Hexapeptide-8 · Acetyl Hexapeptide-3

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A synthetic peptide studied in topical cosmetics for the look of expression lines.

PreliminaryCosmetic & Skin

CJC-1295 (no DAC)

CJC-1295 without DAC · Mod GRF 1-29

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Short-acting modified GHRH analog studied as a pulsatile growth-hormone stimulus.

PreliminaryGrowth Hormone Secretagogues

CJC-1295 with DAC

CJC-1295 DAC · Drug Affinity Complex CJC-1295

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Long-acting GHRH analog studied for sustained growth-hormone elevation.

PreliminaryGrowth Hormone Secretagogues

Dihexa

N-hexanoic-Tyr-Ile-(6) aminohexanoic amide · PNB-0408

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Angiotensin IV-derived peptidomimetic studied in preclinical models for synaptogenesis.

PreliminaryCognitive & Neuro

DSIP (Delta Sleep-Inducing Peptide)

Delta Sleep-Inducing Peptide · Emideltide

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A naturally occurring nonapeptide studied for sleep regulation, with mixed human evidence.

PreliminarySleep & Recovery

FOXO4-DRI

FOXO4-DRI · FOXO4 D-Retro-Inverso peptide

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Senolytic peptide designed to selectively trigger apoptosis in senescent cells.

PreliminaryLongevity & Mitochondrial

GHK (copper-free)

Glycyl-L-Histidyl-L-Lysine · GHK tripeptide

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A naturally occurring human tripeptide studied in skin care in its non-copper-bound form.

PreliminaryCosmetic & Skin

GHRP-6

Growth Hormone Releasing Peptide-6 · SKF-110679

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Early clinically studied GHRP; ghrelin-receptor agonist with marked appetite effect.

PreliminaryGrowth Hormone Secretagogues

Hexarelin

Examorelin · EP-23905

→

Synthetic GHRP analog studied for growth-hormone and cardiovascular effects.

PreliminaryGrowth Hormone Secretagogues

HGH Fragment 176-191

Frag 176-191 · HGH Frag

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A synthetic C-terminal fragment of human growth hormone studied for fat metabolism in research settings.

PreliminaryMetabolic & Weight Management

Humanin

Humanin · HN

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Mitochondrial-derived peptide that acts as a cytoprotective and neuroprotective signal.

PreliminaryLongevity & Mitochondrial

IGF-1 DES

IGF-1 DES(1-3) · DES(1-3) IGF-1

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A truncated analog of IGF-1 studied chiefly in cell and animal models for localized growth signaling.

PreliminaryGrowth Factors & IGF

IGF-1 LR3

Long R3 IGF-1 · Long Arg3 IGF-1

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A long-acting synthetic analog of insulin-like growth factor 1 used chiefly as a research reagent.

PreliminaryGrowth Factors & IGF

Ipamorelin

NNC 26-0161

→

Selective ghrelin-receptor agonist that stimulates a growth-hormone pulse.

PreliminaryGrowth Hormone Secretagogues

Klotho

Klotho protein · alpha-Klotho

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A naturally occurring protein, first linked to aging in mice, studied as a longevity and cognition factor.

PreliminaryLongevity & Mitochondrial

KPV

Lysine-Proline-Valine · α-MSH (11-13)

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Alpha-MSH-derived tripeptide studied for anti-inflammatory effects in the gut and skin.

PreliminaryTissue Repair & Recovery

Lipo-B12 / MIC Injection

Lipotropic injection · MIC

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A compounded lipotropic blend combining methionine, inositol, choline, and vitamin B12.

PreliminaryMetabolic & Weight Management

MGF (Mechano Growth Factor)

Mechano Growth Factor · IGF-1Ec

→

A locally expressed IGF-1 splice variant studied in animal models for muscle repair.

PreliminaryGrowth Factors & IGF

MOTS-c

Mitochondrial ORF of the twelve S rRNA type-c · mitochondrial-derived peptide

→

Mitochondrial-derived peptide researched for metabolic regulation.

PreliminaryMetabolic & Weight Management

P21 (P021)

P021 · P-21

→

Adamantane-modified CNTF-derived tetrapeptide studied for neurogenesis and tau pathology.

PreliminaryCognitive & Neuro

Palmitoyl Tetrapeptide-7

Pal-GQPR · Rigin

→

A synthetic topical lipopeptide studied as an anti-inflammatory, skin-conditioning ingredient in cosmetic formulations.

PreliminaryCosmetic & Skin

Palmitoyl Tripeptide-1

Pal-GHK · Palmitoyl Oligopeptide

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A topical cosmetic peptide studied as a fibroblast-signaling ingredient in anti-aging skincare formulations.

PreliminaryCosmetic & Skin

PE-22-28

Spadin analog · TREK-1 inhibitor peptide

→

Spadin-derived 7-residue peptide studied for antidepressant-like effects via TREK-1.

PreliminaryCognitive & Neuro

PEG-MGF

Pegylated MGF · Pegylated Mechano Growth Factor

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A pegylated, longer-acting form of a muscle-derived IGF-1 splice variant studied mainly in preclinical models.

PreliminaryGrowth Factors & IGF

Pinealon

Pineal bioregulator · EDR peptide

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A synthetic Glu-Asp-Arg tripeptide bioregulator studied in laboratory models for neuroprotection and gene-expression effects.

PreliminaryCognitive & Neuro

Pregnenolone

P5 · 3 beta-hydroxy-5-pregnen-20-one

→

Upstream steroid precursor hormone sold as a supplement with limited evidence.

PreliminaryHormones & TRT/HRT Adjuncts

SLU-PP-332

ERR agonist · exercise mimetic

→

An experimental synthetic ERR agonist studied in animals as an "exercise mimetic" for metabolic pathways.

PreliminaryLongevity & Mitochondrial

TB-500

Thymosin Beta-4 fragment · TB4 synthetic analog

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Synthetic peptide related to thymosin beta-4, studied for cell migration and soft-tissue recovery.

PreliminaryTissue Repair & Recovery

Thymalin

Thymus peptide complex · Thymalinum

→

Calf-thymus peptide complex used in Russia as an immune bioregulator.

PreliminaryImmune & Thymic

Thymogen

Thymagen · Glu-Trp

→

Synthetic dipeptide (Glu-Trp) derived from thymalin as a minimal immune regulator.

PreliminaryImmune & Thymic

Thymulin

Thymulin · Zinc-thymulin

→

Zinc-dependent thymic nonapeptide involved in T-cell maturation and immune signaling.

PreliminaryLongevity & Mitochondrial

Epitalon (Epithalon)

Epitalon · Epithalon

→

Synthetic pineal tetrapeptide studied for telomerase activation and circadian regulation.

AnecdotalLongevity & Mitochondrial

Melanotan II

MT-II · MT2

→

Non-selective melanocortin agonist associated with pigmentation and arousal effects.

AnecdotalSexual & Reproductive Health

N-Acetyl Selank Amidate

NA-Selank Amidate · NA Selank

→

Modified Selank variant engineered for improved enzymatic stability.

AnecdotalCognitive & Neuro

N-Acetyl Semax Amidate

NA-Semax Amidate · NA Semax

→

Chemically modified Semax variant designed for greater stability and longer action.

AnecdotalCognitive & Neuro

Pentadeca Arginate (PDA)

PDA · BPC-157 arginate

→

Arginate-salt form of the BPC-157 sequence sold for healing; lacks its own trial data.

AnecdotalTissue Repair & Recovery

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