Growth Hormone Secretagogues

Hexarelin

Also known as Examorelin · EP-23905 · His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2

PreliminarySubcutaneous injectionIntravenous (research)Not FDA-approved for any indication. Prohibited in sport (WADA, growth hormone secretagogues, S2). Research/compounded use only.

Hexarelin (examorelin) is a synthetic hexapeptide growth hormone-releasing peptide structurally related to GHRP-6, acting on ghrelin/growth hormone secretagogue receptors at the pituitary and hypothalamic levels to release growth hormone. In human studies it also produces slight stimulation of prolactin, ACTH, and cortisol, and it has been investigated for direct cardiovascular receptor effects independent of growth hormone. It is not an approved drug.

Studied / used for

Studied for stimulation of growth hormone release
Investigated for direct cardiovascular and cardioprotective effects in research
Used in research characterizing growth hormone secretagogue receptors

Commonly reported side effects

Injection-site reactions
Mild rises in cortisol, ACTH, and prolactin
Flushing
Headache
Fluid retention
Receptor desensitization with continued exposure reported in research

Preliminary. Mostly early or animal studies. This reflects the strength of the research base, not effectiveness or a recommendation.

Not medical advice.

This is an educational reference. Peptalk does not recommend, prescribe, endorse, or rate any compound, and provides no dosing information. Do not start, stop, or change any peptide, hormone, supplement, or therapy based on this page. All clinical decisions must be made with your licensed healthcare provider.

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