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Tissue Repair & Recovery

BPC-157

Also known as Body Protection Compound 157 · Bepecin · PL 14736 · Pentadecapeptide BPC 157

Emerging researchSubcutaneous injectionIntramuscular injectionOralNot FDA-approved for any indication; treated as an unapproved drug. Was among peptides removed from the FDA interim 503A Category 2 bulks list in April 2026 and is scheduled for Pharmacy Compounding Advisory Committee (PCAC) review beginning July 2026. Prohibited in sport by WADA.

BPC-157 is a synthetic 15-amino-acid peptide derived from a sequence identified in human gastric juice. In preclinical (mostly rodent) studies it has been reported to influence angiogenesis, collagen organization, fibroblast activity, and nitric-oxide pathway signaling, which researchers have associated with healing of muscle, tendon, ligament, bone, nerve, and gastrointestinal tissue and with reduced inflammatory signaling. Human efficacy and safety data are very limited, so most available evidence comes from animal models rather than controlled human trials.

Studied / used for

  • Studied in animal models for tendon, ligament, and muscle healing
  • Studied in animal models for gastrointestinal mucosal healing
  • Investigated in preclinical models for nerve injury repair
  • Studied for anti-inflammatory effects on injured tissue in animal models

Commonly reported side effects

  • Injection-site reactions (redness, swelling, discomfort) reported with injectable use
  • Limited human safety data; long-term effects not well characterized
  • Theoretical concerns related to its angiogenic (blood-vessel-promoting) activity
Emerging research. Active research; human evidence still developing. This reflects the strength of the research base, not effectiveness or a recommendation.

Not medical advice.

This is an educational reference. Peptalk does not recommend, prescribe, endorse, or rate any compound, and provides no dosing information. Do not start, stop, or change any peptide, hormone, supplement, or therapy based on this page. All clinical decisions must be made with your licensed healthcare provider.

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