Growth Hormone Secretagogues

GHRP-6

Also known as Growth Hormone Releasing Peptide-6 · SKF-110679 · His-DTrp-Ala-Trp-DPhe-Lys-NH2

PreliminarySubcutaneous injectionNot FDA-approved for any indication. Not established as a permitted bulk substance for US compounding. Prohibited in sport (WADA, S2). Research/compounded use only.

GHRP-6 is a synthetic hexapeptide and one of the earliest growth hormone-releasing peptides, acting on the ghrelin receptor (GHS-R1a) to stimulate growth-hormone secretion. As an early clinically studied member of the family it helped establish the growth hormone secretagogue pathway. It characteristically causes a pronounced increase in appetite via ghrelin-receptor activation and produces mild increases in cortisol and prolactin. It is not an approved medication.

Studied / used for

Studied historically for stimulation of growth hormone release
Investigated for appetite stimulation
Used in research characterizing the growth hormone secretagogue receptor pathway

Commonly reported side effects

Marked increase in appetite/hunger
Injection-site reactions
Mild rises in cortisol and prolactin
Flushing
Headache
Water retention

Preliminary. Mostly early or animal studies. This reflects the strength of the research base, not effectiveness or a recommendation.

Not medical advice.

This is an educational reference. Peptalk does not recommend, prescribe, endorse, or rate any compound, and provides no dosing information. Do not start, stop, or change any peptide, hormone, supplement, or therapy based on this page. All clinical decisions must be made with your licensed healthcare provider.

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