Sexual & Reproductive Health

HCG (Human Chorionic Gonadotropin)

Also known as hCG · Human Chorionic Gonadotropin · Pregnyl · Novarel

Clinically studiedSubcutaneous injectionIntramuscular injectionFDA-approved for certain forms of hypogonadism and reproductive indications; weight-loss claims are not FDA-approved

Human chorionic gonadotropin (HCG) is a glycoprotein hormone structurally and functionally similar to luteinizing hormone (LH). It stimulates the testes (Leydig cells) to produce testosterone and supports spermatogenesis, and it stimulates ovulation in women. In men it has been studied to help preserve testicular function and fertility, including alongside testosterone therapy.

Studied / used for

Studied for hypogonadotropic hypogonadism in men
Studied for preserving fertility and testicular size during TRT
Studied for inducing ovulation in women

Commonly reported side effects

Headache
Irritability or restlessness
Injection-site pain, redness or swelling
Gynecomastia
Nausea
Fluid retention

Clinically studied. Supported by human clinical trials. This reflects the strength of the research base, not effectiveness or a recommendation.

Not medical advice.

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